Monday, January 30, 2012

Clinical Trials for Organ Transplantation in Children Programme

By Michael Saunders


The National Institutes of Health, more generally known as NIH, is a federal government agency operating within the United States Department of Health and Human Services that is significantly responsible for pursuing and encouraging the country's biomedical and health-related research studies.

The programs and grants of the NIH are all aimed towards the achievement of its overall agency mission which is to "seek basic knowledge of the nature and behaviour of living systems and the application of that information to enhance health, lengthen life, and scale back the burdens of illness and disability."

In accordance with this mission, the National Insitutes of Health has formed a partnership with the National Institute of Allergy and Infectious Diseases (NIAID) to establish the Clinical Trials for Organ Transplantation in Children Program whereby both agencies propose to support a group of investigators in their quest of conducting clinical trials regarding pediatric solid organ transplant recipients.

The clinical trials that will be covered under the program can be done in conjunction with observational clinical trials and mechanistic studies. The trials can be in its first, second or 3rd phase and should target pediatric solid organ transplant recipients, that is patients who have undergone heart, liver,lung, small intestine, or kidney transplantation before they turned 21 years old.

In a larger scope, the initiatives of the program will focus on reducing or alleviating cases of long term graft dysfunction and immune-mediated morbidity and mortality that's exclusive to pediatric solid organ transplant patients.

The NIH and the National Institute of Allergy and Infectious Diseases are ready to administer a total funding amount of $4,300,000 to three to four admissible grant participants.

The institutions and associations who will be permitted to submit an application under this programme are the following:

a) Higher Education Institutions such as Public/State Controlled Institutions of Higher Education and Private Institutions of Higher Education

b) Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions

c) Non-profit organizations aside from institutions of higher education

d) For-Profit Organizations such as Small Businesses

e) State Governments, County Governments, City or Township Governments, Special District Governments, Indian/Native American Tribal Governments (Federally Recognized), and Indian/Native American Tribal Governments (Apart from Federally Recognized)

f) Independent School Districts, Public Housing Authorities/Indian Housing Authorities, Native American Tribal Setups (aside from Federally recognized tribal governments), Faith-based or Community-based Organizations, and Regional Organizations.




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